Journal article

International survey of human herpes virus 8 screening and management in solid organ transplantation

Alessandra Mularoni, Malgorzata Mikulska, Maddalena Giannella, Lucia Adamoli, Monica Slavin, Christian Van Delden, Jose Maria Aguado Garcia, Carlos Cervera, Paolo Antonio Grossi

TRANSPLANT INFECTIOUS DISEASE | WILEY | Published : 2021

Abstract

BACKGROUND: HHV-8/Kaposi Sarcoma herpesvirus has been associated with a broad spectrum of diseases in solid organ transplant (SOT) recipients. Primary donor-derived infection can be associated with severe and rapidly fatal non-neoplastic disease, and diagnosis is made with high HHV-8 DNAemia. METHODS: We carried out an international survey to investigate the current approach to HHV-8 screening, and management in SOT since a protocol has not been established by international guidelines. RESULTS: A total of 51 transplant centers from 15 countries filled out the survey. HHV-8-associated diseases in SOT have been diagnosed during the previous 5 years in 67% of centers. Pretransplant serological ..

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