Journal article

International survey of human herpes virus 8 screening and management in solid organ transplantation

Alessandra Mularoni, Malgorzata Mikulska, Maddalena Giannella, Lucia Adamoli, Monica Slavin, Christian Van Delden, Jose Maria Aguado Garcia, Carlos Cervera, Paolo Antonio Grossi



BACKGROUND: HHV-8/Kaposi Sarcoma herpesvirus has been associated with a broad spectrum of diseases in solid organ transplant (SOT) recipients. Primary donor-derived infection can be associated with severe and rapidly fatal non-neoplastic disease, and diagnosis is made with high HHV-8 DNAemia. METHODS: We carried out an international survey to investigate the current approach to HHV-8 screening, and management in SOT since a protocol has not been established by international guidelines. RESULTS: A total of 51 transplant centers from 15 countries filled out the survey. HHV-8-associated diseases in SOT have been diagnosed during the previous 5 years in 67% of centers. Pretransplant serological ..

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