Journal article

Informed choice and attitudes regarding a genomic test to predict risk of colorectal cancer in general practice

S Saya, JG McIntosh, IM Winship, S Milton, M Clendenning, M Kyriakides, J Oberoi, DD Buchanan, MA Jenkins, JD Emery

Patient Education and Counseling | ELSEVIER IRELAND LTD | Published : 2022

Abstract

Objective: A genomic test to predict personal risk of colorectal cancer (CRC) that targets screening and could be feasibly implemented in primary care. We explored informed decision-making and attitudes towards genomic testing in this setting. Methods: A CRC genomic test was offered to 150 general practice patients with brief discussion of its implications. We measured informed choice about the test, consisting knowledge, attitudes and test uptake. Sixteen purposively-sampled participants were interviewed. Results: Of 150, 142 (95%) completed the informed choice measure and of 27 invited, 16 (59%) completed an interview. 73% made an informed choice about the test. Interviews revealed that pa..

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Grants

Awarded by Cancer Research UK


Funding Acknowledgements

This study was supported by the Primary Care Collaborative Cancer Clinical Trials Group (PC4). This research is linked to the CanTest Collaborative, which is funded by Cancer Research UK [C8640/A23385], of which JDE is Associate Director. SS is supported by an Australian Government Research Training Program (RTP) Scholarship. JDE is supported by an NHMRC Practitioner Fellowship. MAJ is an NHMRC Senior Research Fellow. The authors' funders played no part in the design, analysis, or drafting of this manuscript.