Journal article

Prodromal symptoms of Chinese patients with bipolar disorder

Tong Guo, Yuan Yang, Qian Zhao, Lei Zhang, Chee H Ng, Teris Cheung, Yang Li, Xue-Quan Zhu, Xiao-Hong Li, Yu-Tao Xiang

JOURNAL OF AFFECTIVE DISORDERS | ELSEVIER | Published : 2021

Abstract

OBJECTIVE: This study aimed to assess the clinical phenomenology and characteristics of prodromal symptoms in Chinese patients with bipolar disorder (BPD) prior to their index mood episode. METHODS: Semi-structured interviews [Bipolar Prodrome Symptom Scale-Retrospective (BPSS-R)] were administered to patients within 3 years of BPD (I and II) onset. RESULTS: 120 stable inpatients and outpatients were included (65% males, mean age: 26.5±10.0 years). Feeling extremely energetic (61.8%), overly cheerful (49.1%), racing thoughts (48.2%), overly talkative (47.3%), and decreased need for sleep (43.6%) most frequently preceded the first (hypo)manic episode, whereas depressed mood (78.5%), tiredness..

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University of Melbourne Researchers

Grants

Awarded by Capital City Clinical Practice and Research Funding of Beijing Municipal Science & Technology Commission


Awarded by National Key Research & Development Program of China


Awarded by University of Macau


Funding Acknowledgements

The study was supported by the Capital City Clinical Practice and Research Funding of Beijing Municipal Science & Technology Commission (Z151100004015042), National Key Research & Development Program of China (No. 2016YFC1307200), and the University of Macau (MYRG2015-00230-FHS; MYRG2016-00005-FHS).