Journal article

Reducing asthma hospitalisations in at-risk children: A systematic review

Katherine YH Chen, Leanne Saxon, Colin Robertson, Harriet Hiscock



AIM: To identify interventions that reduce hospitalisations and improve related outcomes in children at risk of asthma hospital admissions. METHODS: Medline, Embase, Pubmed and Cochrane Library search from January 2002 to April 2020. INCLUSION CRITERIA: randomised controlled trials of any intervention for children with asthma who are at risk of hospitalisations. OUTCOMES: hospitalisation (primary outcome), rescue oral corticosteroid use, school absences, quality of life and cost-effectiveness. RESULTS: Twelve randomised controlled trials were conducted with 2719 participants. Due to heterogeneity of interventions and reporting of outcomes, a meta-analysis was not conducted. Multi-modal inter..

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Awarded by NHMRC

Funding Acknowledgements

The authors would like to thank Associate Professor Susan Donath from the Murdoch Children's Research Institute and the University of Melbourne for her advice regarding statistical methods and Ms Poh Chua for the Royal Children's Hospital library services for her assistance with the literatures search. The study is supported by the Melbourne Academic Centre of Health. The Murdoch Children's Research Institute is funded through Victorian Operating Fund. HH holds a NHMRC Practitioner fellowship grant GN1136222. These entities had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, and approval of the manuscript; or decision to submit the manuscript for publication.