Impaired Weight-Shift Amplitude in People with Parkinson's Disease with Freezing of Gait
Bauke W Dijkstra, Moran Gilat, L Eduardo Cofre Lizama, Martina Mancini, Bruno Bergmans, Sabine MP Verschueren, Alice Nieuwboer
JOURNAL OF PARKINSONS DISEASE | IOS PRESS | Published : 2021
BACKGROUND: People with Parkinson's disease and freezing of gait (FOG; freezers) suffer from pronounced postural instability. However, the relationship between these phenomena remains unclear and has mostly been tested in paradigms requiring step generation. OBJECTIVE: To determine if freezing-related dynamic balance deficits are present during a task without stepping and determine the influence of dopaminergic medication on dynamic balance control. METHODS: Twenty-two freezers, 16 non-freezers, and 20 healthy age-matched controls performed mediolateral weight-shifts at increasing frequencies when following a visual target projected on a screen (MELBA task). The amplitude and phase shift dif..View full abstract
Awarded by Research Foundation Flanders (FWO)
Awarded by European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant
BWD was supported by the Research Foundation Flanders (FWO, grant number G.0867.15). MG received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 838576.