Journal article
Predicting factors for central or lateral lymph node metastasis in conventional papillary thyroid microcarcinoma
Lei Sheng, Jinyuan Shi, Bo Han, Bin Lv, Luchuan Li, Bo Chen, Nan Liu, Yingting Cao, Andrew G Turner, Qingdong Zeng
AMERICAN JOURNAL OF SURGERY | EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC | Published : 2020
Abstract
BACKGROUND: Optimal management for papillary thyroid microcarcinoma (PTMC) remains controversial. The purpose of this study was to explore risk factors predictive of cervical lymph node metastasis in conventional PTMCs. METHODS: Conventional PTMC patients (n = 2,404) undergoing surgery between 2010 and 2017 were grouped and analyzed according to the positivity of cervical lymph node. RESULTS: Central lymph node (CLN) metastases and lateral lymph node (LLN) metastases were observed in 915 (38.1%) and 184 (7.7%) cases, respectively. Multivariate analysis found that male (odds ratio [OR] = 1.974, p < 0.001), younger age (OR = 1.601, p < 0.001), tumor size (OR = 1.935, p < 0.001), extrathyroidal..
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Awarded by National Natural Science Foundation of China
Funding Acknowledgements
This work was supported by the National Natural Science Foundation of China (Grant NO. 81802642).