Demographic and lifestyle risk factors for gastroesophageal reflux disease and Barrett's esophagus in Australia.
Sabrina E Wang, Bradley J Kendall, Allison M Hodge, Suzanne C Dixon-Suen, S Ghazaleh Dashti, Enes Makalic, Elizabeth M Williamson, Robert JS Thomas, Graham G Giles, Dallas R English
Dis Esophagus | Published : 2021
We examined demographic and lifestyle risk factors for incidence of gastroesophageal reflux disease (GERD) and Barrett's esophagus (BE) in an Australian cohort of 20,975 participants aged 40-63 at recruitment (1990-1994). Information on GERD and BE was collected between 2007 and 2010. GERD symptoms were defined as self-reported heartburn or acid regurgitation. BE was defined as endoscopically confirmed columnar-lined esophagus. Risk factors for developing GERD symptoms, BE diagnosis, age at symptom onset, and age at BE diagnosis were quantified using regression. During a mean follow-up of 15.8 years, risk of GERD symptoms was 7.5% (n = 1,318) for daily, 7.5% (n = 1,333) for 2-6 days/week, an..View full abstract
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