Regenerative Medicine: A Programmed Anti‐Inflammatory Nanoscaffold (PAIN) as a 3D Tool to Understand the Brain Injury Response (Adv. Mater. 50/2018)

Abstract

The inflammatory environment post injury is a key mechanism in guiding regeneration. However, reproducing this process is a significant biological challenge. In article number 1805209, Richard J. Williams, David R. Nisbet, and co‐workers demonstrate a nanostructured scaffold that can sustain astrocytes in long‐term culture; then, using nanobiotechnology, they switch inflammation on or off in a programmed fashion to simulate the response to healthy or damaged tissue.