Journal article

Use of emerging testing technologies and approaches for SARS-CoV-2: review of literature and global experience in an Australian context

Maryza Graham, Susan A Ballard, Shivani Pasricha, Belinda Lin, Tuyet Hoang, Timothy Stinear, Julian Druce, Mike Catton, Norelle Sherry, Deborah Williamson, Benjamin P Howden

PATHOLOGY | ELSEVIER | Published : 2021


Emerging testing technologies for detection of SARS-CoV-2 include those that are rapid and can be used at point-of-care (POC), and those facilitating high throughput laboratory-based testing. Tests designed to be performed at POC (such as antigen tests and molecular assays) have the potential to expedite isolation of infectious patients and their contacts, but most are less sensitive than standard-of-care reverse transcription polymerase chain reaction (RT-PCR). Data on clinical performance of the majority of emerging assays are limited with most evaluations performed on contrived or stored laboratory samples. Further evaluations of these assays are required, particularly when performed at P..

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Funding Acknowledgements

This work was supported by the Australian Government Department of Health Medical Research Future Fund (MRFF) COVID-19 diagnostics grant provided to the Peter Doherty Institute for Infection and Immunity. The authors state that there are no conflicts of interest to disclose.