Journal article

Multi-Omic Analysis of Symbiotic Bacteria Associated With Aedes aegypti Breeding Sites

Katherine D Mosquera, Luis E Martinez Villegas, Sacha J Pidot, Chinhda Sharif, Sven Klimpel, Timothy P Stinear, Luciano A Moreira, Nicholas J Tobias, Marcelo G Lorenzo



Mosquito breeding sites are complex aquatic environments with wide microbial diversity and physicochemical parameters that can change over time during the development of immature insect stages. Changes in biotic and abiotic conditions in water can alter life-history traits of adult mosquitos but this area remains understudied. Here, using microbial genomic and metabolomics analyses, we explored the metabolites associated with Aedes aegypti breeding sites as well as the potential contribution of Klebsiella sp., symbiotic bacteria highly associated with mosquitoes. We sought to address whether breeding sites have a signature metabolic profile and understand the metabolite contribution of the b..

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Awarded by Fundacao de Amparo a Pesquisa do Estado de Minas Gerais FAPEMIG

Awarded by CNPq

Awarded by INCTEM

Funding Acknowledgements

This work was funded by the LOEWE-Centre TBG supported by the Hessen State Ministry of Higher Education, Research and the Arts (HMWK), Fundacao de Amparo a Pesquisa do Estado de Minas Gerais FAPEMIG - EDITAL 00/2016 - CONFAP - MRC/TEC - APQ-00913-16, CNPq (Project number: 311826/2019-9), INCTEM (Project number: 465678/20149), and FIOCRUZ.