Journal article
Birthweight-for-gestational-age z-scores are associated with early childhood cardiometabolic health in the Peri/Postnatal Epigenetic Twin Study
DN Ashtree, MJ Silva, C Sun, JM Craig, KJ Scurrah
Journal of Developmental Origins of Health and Disease | CAMBRIDGE UNIV PRESS | Published : 2022
Abstract
Birthweight has been consistently related to risk of cardiometabolic disorders in later life. Twins are at higher risk of low birthweight than singletons, so understanding the links between birthweight and cardiometabolic health may be particularly important for twins. However, evidence for the association of birthweight with childhood markers of cardiometabolic health in twins is currently lacking. Previous studies have often failed to appropriately adjust for gestational age or fully implement twin regression models. Therefore, we aimed to evaluate the association of birthweight-for-gestational-age z-scores with childhood cardiometabolic health in twins, using within-between regression mod..
View full abstractGrants
Awarded by Australian National Health and Medical Research Council
Awarded by Bonnie Babes Foundation
Awarded by Financial Markets Foundation for Children
Funding Acknowledgements
This work was supported by the Australian Government Research Training Program (D.A.); Twins Research Australia, which receives support from the National Health and Medical Research Council through a Centre of Research Excellence Grant, administered by the University of Melbourne (K.S.); the Australian National Health and Medical Research Council (J.C., grant numbers 437015 and 607358); the Bonnie Babes Foundation (J.C., grant number BBF20704); the Financial Markets Foundation for Children (J.C., grant number 032-2007) and the Victorian Government's Operational Infrastructure Support Program.