Risks of recurrent stroke and all serious vascular events after spontaneous intracerebral haemorrhage: pooled analyses of two population-based studies
Linxin Li, Michael TC Poon, Neshika E Samarasekera, Luke A Perry, Tom J Moullaali, Mark A Rodrigues, James JM Loan, Jacqueline Stephen, Christine Lerpiniere, Maria A Tuna, Sergei A Gutnikov, Wilhelm Kuker, Louise E Silver, Rustam Al-Shahi Salman, Peter M Rothwell
LANCET NEUROLOGY | ELSEVIER SCIENCE INC | Published : 2021
BACKGROUND: Patients with stroke due to spontaneous (non-traumatic) intracerebral haemorrhage (ICH) are at risk of recurrent ICH, ischaemic stroke, and other serious vascular events. We aimed to analyse these risks in population-based studies and compare them with the risks in RESTART, which assessed antiplatelet therapy after ICH. METHODS: We pooled individual patient data from two prospective, population-based inception cohort studies of all patients with an incident firs-in-a-lifetime ICH in Oxfordshire, England (Oxford Vascular Study; April 1, 2002, to Sept 28, 2018) and Lothian, Scotland, UK (Lothian Audit of the Treatment of Cerebral Haemorrhage; June 1, 2010, to May 31, 2013). We quan..View full abstract
UK Medical Research Council, Stroke Association, British Heart Foundation, Wellcome Trust, and the National Institute for Health Research Oxford Biomedical Research Centre.