Risk factors for surgical site infection in free-flap reconstructive surgery for head and neck cancer: A retrospective Australian cohort study.
Peter Francis Gearing, John Frederick Daly, Nicholas Shi Jie Tang, Kasha Singh, Anand Ramakrishnan
Head Neck | Published : 2021
BACKGROUND: Surgical site infections (SSI) are common complications of free-flap reconstruction for head and neck cancer defects. This study aimed to identify risk factors for SSI following a significant change in local antibiotic prophylaxis practice. METHODS: A retrospective cohort study was conducted of 325 patients receiving free-flap reconstruction for head and neck cancer defects at a tertiary hospital in Melbourne, Australia between 2013 and 2019. Charts were queried for recipient SSI (primary outcome), donor SSI, other infections, antibiotic use, hospital length of stay, and mortality. RESULTS: Risk factors for SSI included female sex, T-classification, hardware insertion, clindamyci..View full abstract