S72. FUNCTIONAL DISCONNECTION WITHIN THE PRESENCE HALLUCINATION NETWORK IN PSYCHOTIC PATIENTS WITH FIRST-RANK SYMPTOMS

Abstract

Abstract Background Psychosis is an abnormal mental state including hallucinations and delusions, typical of psychiatric conditions such as schizophrenia. Recent theories posit that psychosis is driven by inaccurate sensorimotor predictions causing the misattribution of self-related events to external sources. This misattribution has been linked to first-rank symptoms (FRS), including a loss of sense of agency and, particularly, the occurrence of an alien agent. The subjective experience of an alien agent while no one is actually there is called presence hallucination (PH). PH has been observed in schizophrenia, Parkinson’s disease and neurological patients with circumscribed brain lesions. ..