Journal article

Longitudinal prediction of periconception alcohol use: a 20-year prospective cohort study across adolescence, young adulthood and pregnancy

Delyse Hutchinson, Elizabeth A Spry, Hanafi Mohamad Husin, Melissa Middleton, Stephen Hearps, Margarita Moreno-Betancur, Elizabeth J Elliott, Joanne Ryan, Craig A Olsson, George C Patton

ADDICTION | WILEY | Published : 2021


BACKGROUND AND AIMS: Alcohol consumption is common in adolescence and young adulthood and may continue into pregnancy, posing serious risk to early fetal development. We examine the frequency of periconception alcohol use (prior to pregnancy awareness) and the extent to which adolescent and young adult alcohol use prospectively predict periconception use. DESIGN: A longitudinal, population-based study. SETTING: Victoria, Australia. PARTICIPANTS: A total of 289 women in trimester three of pregnancy (age 29-35 years; 388 pregnancies). MEASURES: The main exposures were binge [≥ 4.0 standard drinks (SDs)/day] and frequent (≥ 3 days/week) drinking in adolescence (mean age = 14.9-17.4 years) and y..

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Awarded by National Health and Medical Research Council

Awarded by Australian Research Council

Funding Acknowledgements

This work was supported by the National Health and Medical Research Council [APP1008273, APP1063091, APP437015, APP1019887 to G.P., APP1110341 to E.E., APP1197488 to D.H., APP1175086 to C.O.]; Australian Rotary Health; Colonial Foundation; Perpetual Trustees; Financial Markets Foundation for Children (Australia); Royal Children's Hospital Foundation; Murdoch Children's Research Institute; Australian Postgraduate Award to E.S.; and the Australian Research Council (DP180102447, DP1311459 to C.O. and DE190101326 to M.M-B.) Research at the Murdoch Children's Research Institute is supported by the Victorian Government's Operational Infrastructure Program. Both the Victorian Adolescent Health Cohort Study (VAHCS) and the Victorian Intergenerational Health Cohort Study (VIHCS) have been supported by a series of project grants from Australia's National Health and Medical Research Council (NHMRC), the Victorian Health Promotion Foundation, the Colonial Foundation, Australian Rotary Health, Perpetual Trustees and Financial Markets for Children (Australia). We thank the families who participated in VAHCS and VIHCS; the study research team involved in data collection and management; and Professor Anthony Mann and Professor Sir Michael Rutter for advice on study design. The funders had no role in the design and conduct of the study; collection, management, analysis and interpretation of the data; preparation, review or approval of the manuscript; and decision to submit the manuscript for publication.