Optical Coherence Tomography of Coronary Plaque Progression and Destabilization
Tom Adriaenssens, Marc P Allard-Ratick, Vikas Thondapu, Tomoyo Sugiyama, O Christopher Raffel, Peter Barlis, Eric KW Poon, Makoto Araki, Akihiro Nakajima, Yoshiyasu Minami, Masamichi Takano, Osamu Kurihara, Valentin Fuster, Tsunekazu Kakuta, Ik-Kyung Jang
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | ELSEVIER SCIENCE INC | Published : 2021
The development of optical coherence tomography (OCT) has revolutionized our understanding of coronary artery disease. In vivo OCT research has paralleled with advances in computational fluid dynamics, providing additional insights in the various hemodynamic factors influencing plaque growth and stability. Recent OCT studies introduced a new concept of plaque healing in relation to clinical presentation. In addition to known mechanisms of acute coronary syndromes such as plaque rupture and plaque erosion, a new classification of calcified plaque was recently reported. This review will focus on important new insights that OCT has provided in recent years into coronary plaque development, prog..View full abstract
Dr Jang's research was supported by the Allan Gray Fellowship Fund and by Mr. and Mrs. Michael and Kathryn Park. Dr. Adriaenssens has received educational grants from Abbott Vascular. Dr Jang has received educational grants from Abbott Vascular; and has received consulting fees from Svelte Medical Systems Inc. and Mitobridge Inc. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.