Journal article

Performance-driven design of biocompatible Mg alloys

NT Kirkland, MP Staiger, D Nisbet, CHJ Davies, N Birbilis

JOM | Published : 2011


Magnesium (Mg) and its alloys provide numerous benefits as a resorptive biomaterial and present the very real possibility of replacing current metallic implant materials in a variety of roles. The development of suitable biodegradable implant alloys is a multidisciplinary challenge, since alloy design must be confined to a range of alloying additions that are biologically nontoxic, whilst still providing the requisite mechanical properties. This leaves a small number of compatible elements that can provide benefits when alloyed with Mg, including calcium (Ca) and zinc (Zn). To date, although a range of different Mg alloys have been investigated both in vitro and in vivo, little work has been..

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