Journal article
Factors associated with severe respiratory syncytial virus disease in hospitalised children: a retrospective analysis
J Anderson, M Oeum, E Verkolf, PV Licciardi, K Mulholland, C Nguyen, K Chow, G Waller, AM Costa, A Daley, NW Crawford, FE Babl, T Duke, LAH Do, D Wurzel
Archives of Disease in Childhood | BMJ PUBLISHING GROUP | Published : 2022
Abstract
Background Early recognition of children at risk of severe respiratory syncytial virus (RSV) lower respiratory tract infection is important as it informs management decisions. We aimed to evaluate factors associated with severe disease among young children hospitalised with RSV infection. Methods We conducted a retrospective cohort study of all children <2 years of age hospitalised for RSV lower respiratory tract infection at a single tertiary paediatric hospital over three RSV seasons (January 2017–December 2019). We classified children as having’moderate’ or’severe’ disease based on the level of respiratory intervention and used univariable and multivariable regression models to determine ..
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Awarded by Murdoch Children's Research Institute
Funding Acknowledgements
This work was funded by the Murdoch Children's Research Institute Theme Research Grant. JA is supported by an Australian Postgraduate Award Scholarship. PVL is a recipient of an Australian National Health and Medical Research Council Career Development Fellowship (GNT1146198). We also thank Victorian Government's Operational Infrastructure Support Program. FEB is a recipient of a National Health and Medical Research Council Practitioner Fellowship and a grant from The Royal Children's Hospital Foundation.