Factors associated with severe respiratory syncytial virus disease in hospitalised children: a retrospective analysis.
Jeremy Anderson, Michelle Oeum, Eva Verkolf, Paul V Licciardi, Kim Mulholland, Cattram Nguyen, Kim Chow, Gregory Waller, Anna-Maria Costa, Andrew Daley, Nigel W Crawford, Franz E Babl, Trevor Duke, Lien Anh Ha Do, Danielle Wurzel
Arch Dis Child | Published : 2021
BACKGROUND: Early recognition of children at risk of severe respiratory syncytial virus (RSV) lower respiratory tract infection is important as it informs management decisions. We aimed to evaluate factors associated with severe disease among young children hospitalised with RSV infection. METHODS: We conducted a retrospective cohort study of all children <2 years of age hospitalised for RSV lower respiratory tract infection at a single tertiary paediatric hospital over three RSV seasons (January 2017-December 2019). We classified children as having 'moderate' or 'severe' disease based on the level of respiratory intervention and used univariable and multivariable regression models to determ..View full abstract