Journal article

Luminescent Metal-Phenolic Networks for Multicolor Particle Labeling

Zhixing Lin, Jiajing Zhou, Yijiao Qu, Shuaijun Pan, Yiyuan Han, Rene PM Lafleur, Jingqu Chen, Christina Cortez-Jugo, Joseph J Richardson, Frank Caruso

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | WILEY-V C H VERLAG GMBH | Published : 2021

Abstract

The development of fluorescence labeling techniques has attracted widespread interest in various fields, including biomedical science as it can facilitate high-resolution imaging and the spatiotemporal understanding of various biological processes. We report a supramolecular fluorescence labeling strategy using luminescent metal-phenolic networks (MPNs) constructed from metal ions, phenolic ligands, and common and commercially available dyes. The rapid labeling process (<5 min) produces ultrathin coatings (≈10 nm) on diverse particles (e.g., organic, inorganic, and biological entities) with customized luminescence (e.g., red, blue, multichromatic, and white light) simply through the selectio..

View full abstract

Grants

Awarded by Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology


Awarded by National Health and Medical Research Council Senior Principal Research Fellowship


Awarded by Netherlands Organisation for Scientific Research


Awarded by JSPS KAKENHI


Awarded by JSPS


Funding Acknowledgements

This research was conducted and funded by the Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology (project number CE140100036). F.C. acknowledges the award of a National Health and Medical Research Council Senior Principal Research Fellowship (GNT1135806). R.P.M.L. acknowledges the Netherlands Organisation for Scientific Research for a Rubicon postdoctoral fellowship (project 019.182EN.034). J.J.R. acknowledges JSPS KAKENHI Grant Number 20F20373 and JSPS Fellowship P20373. This work was performed in part at the Materials Characterisation and Fabrication Platform, Biosciences Microscopy Unit, and Ian Holmes Imaging Centre, Bio21 Institute at The University of Melbourne, and the Victorian Node of the Australian National Fabrication Facility. The authors acknowledge Yingjie Hu, Jiaying Song, and Sukhvir Kaur Bhangu for helpful discussions.