Reliability and Convergent Construct Validity of Quantitative Ultrasound for Synovitis, Meniscal Extrusion, and Osteophyte in Knee Osteoarthritis With MRI

Win Min Oo; James M Linklater; Kim L Bennell; Matthew S Daniel; Danielle Pryke; Xia Wang; Shirley P Yu; Leticia Deveza; Vicky Duong; David J Hunter

Journal article

Reliability and Convergent Construct Validity of Quantitative Ultrasound for Synovitis, Meniscal Extrusion, and Osteophyte in Knee Osteoarthritis With MRI

Win Min Oo, James M Linklater, Kim L Bennell, Matthew S Daniel, Danielle Pryke, Xia Wang, Shirley P Yu, Leticia Deveza, Vicky Duong, David J Hunter

JOURNAL OF ULTRASOUND IN MEDICINE | WILEY | Published : 2021

DOI: 10.1002/jum.15840

Abstract

AIMS: To determine: 1) inter-rater reliability of quantitative measurements of ultrasound-detected synovitis, meniscal extrusion, and osteophytes; and 2) construct (convergent) validity via correlations and absolute agreements between ultrasound- and gold-standard magnetic resonance imaging (MRI)-outcomes in knee osteoarthritis. METHODS: Dynamic ultrasound images for supra-patellar synovitis, meniscal extrusion, and osteophytes were acquired and quantified by a physician operator, musculoskeletal ultrasonographer, and medical student independently. On the same day, 3T MRI images were acquired. Effusion-synovitis, meniscal extrusion, and osteophytes were quantified on sagittal or coronal prot..

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University of Melbourne Researchers

Kim Bennell Author Physiotherapy

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Grants

Awarded by National Health and Medical Research Council

Awarded by NHMRC

Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

This study was funded by the National Health and Medical Research Council (ID: 1106274). We acknowledge Canon Medical Systems for providing the Toshiba ultrasound machine and the study participants. Win Min Oo is supported by a Presidential scholarship of Myanmar for his PhD course. DJH is supported by an NHMRC Investigator Grant (1194737), KLB is supported by an NHMRC Investigator grant (#1174431), SY is supported by the University of Sydney Postgraduate Scholarship (Merck PhD Scholarship in Medicine), VD is supported by a University of Sydney Postgraduate Award scholarship.