Journal article
Viability of a MSQOL-54 general health-related quality of life score using bifactor model
A Giordano, S Testa, M Bassi, S Cilia, A Bertolotto, ME Quartuccio, E Pietrolongo, M Falautano, M Grobberio, C Niccolai, B Allegri, RG Viterbo, P Confalonieri, AM Giovannetti, E Cocco, MG Grasso, A Lugaresi, E Ferriani, U Nocentini, M Zaffaroni Show all
Health and Quality of Life Outcomes | Published : 2021
Abstract
Background: MSQOL-54 is a multidimensional, widely-used, health-related quality of life (HRQOL) instrument specific for multiple sclerosis (MS). Findings from the validation study suggested that the two MSQOL-54 composite scores are correlated. Given this correlation, it could be assumed that a unique total score of HRQOL may be calculated, with the advantage to provide key stakeholders with a single overall HRQOL score. We aimed to assess how well the bifactor model could account for the MSQOL-54 structure, in order to verify whether a total HRQOL score can be calculated. Methods: A large international database (3669 MS patients) was used. By means of confirmatory factor analysis, we estima..
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