Population level outcomes of advancements in diabetes care

Abstract

The development of diabetes-related complications is a major healthcare problem. The overall aim of this thesis is to document trends in the incidence of diabetes-related complications, focusing on those related to cardiovascular and renal disease. Diabetes care has improved significantly over past decades, resulting in improved glycaemic control and an increase in the number of patients achieving various metabolic goals. Indeed, the application of multifactorial, target driven interventions has been shown to reduce the development and progression of diabetes related complications in the clinical trial setting. Furthermore, novel glucose lowering medications have recently been shown to reduc..