Protein levels, air pollution and vitamin D deficiency: links with allergy

Yong Song; E Haydn Walters; Michael J Abramson; Gayan Bowatte; Dinh S Bui; Jennifer Perret; Iain Feather; Luke D Knibbs; Richard Wilson; David S Nichols; Shyamali C Dharmage; Graeme R Zosky

Journal article

Protein levels, air pollution and vitamin D deficiency: links with allergy

Yong Song, E Haydn Walters, Michael J Abramson, Gayan Bowatte, Dinh S Bui, Jennifer Perret, Iain Feather, Luke D Knibbs, Richard Wilson, David S Nichols, Shyamali C Dharmage, Graeme R Zosky

ERJ OPEN RESEARCH | EUROPEAN RESPIRATORY SOC JOURNALS LTD | Published : 2021

DOI: 10.1183/23120541.00237-2021

Abstract

This study provides novel insights into mechanisms of traffic-related air pollution-induced allergy by down-regulation via complement regulators (CFI, PROS1 and PLG) and its interaction with vitamin D deficiency via the complement inhibitor PLG https://bit.ly/3x0jYOw.

University of Melbourne Researchers

Dinh Bui Author Melbourne School of Population and Global Health

Shyamali Dharmage Author Melbourne School of Population and Global Health

Jennifer Perret Author Melbourne School of Population and Global Health

Gayan Bowatte Author Melbourne School of Population and Global Health

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Grants

Awarded by National Health and Medical Research Council (NHMRC) of Australia under the NHMRC project grant scheme

Awarded by National Health and Medical Research Council (NHMRC) of Australia under NHMRC European collaborative grant scheme, ALEC (Ageing Lungs in European Cohorts) (European Union's Horizon 2020 research and innovation programme)

Funding Acknowledgements

Tasmanian Longitudinal Health Study was supported by the National Health and Medical Research Council (NHMRC) of Australia under the NHMRC project grant scheme (299901 and 1021275) and NHMRC European collaborative grant scheme (1101313) as part of ALEC (Ageing Lungs in European Cohorts) (funded by the European Union's Horizon 2020 research and innovation programme under grant agreement number 633212); The University of Melbourne; Clifford Craig Medical Research Trust of Tasmania; the Victorian, Queensland and Tasmanian Asthma Foundations; The Royal Hobart Hospital; Helen MacPherson Smith Trust; and GlaxoSmithKline. S.C. Dharmage, J. Perret and E.H. Walters are supported by the NHMRC of Australia. Funding information for this article has been deposited with the Crossref Funder Registry.