Ultrasound findings and detection of fetal abnormalities before 11 weeks of gestation

Abstract

Objective: To determine the proportion of major fetal structural abnormalities that can be detected before 11 gestational weeks. Methods: We conducted a retrospective study of individual patient files at a tertiary provider of obstetric and gynecological ultrasound in Melbourne, Australia. All women who had a pre-cell-free DNA ultrasound with a crown-rump length of less than 45 mm and had one or more ultrasounds at a later gestation were included in the analysis. The primary outcome was the incidence of a fetal structural abnormality. Results: A total of 3333 cases were included in the final analysis. Overall, 316 fetuses (9.5%) had a structural abnormality detected at any point throughout g..