Incidence of post-traumatic epilepsy following paediatric traumatic brain injury: protocol for systematic review and meta-analysis
Frederick P Mariajoseph, Sarah S Rewell, Terence J O'Brien, Bridgette D Semple, Ana Antonic-Baker
BMJ OPEN | BMJ PUBLISHING GROUP | Published : 2021
INTRODUCTION: Post-traumatic epilepsy (PTE) is a recognised complication of traumatic brain injury (TBI), and is associated with higher rates of mortality and morbidity when compared with patients with TBI who do not develop PTE. The majority of the literature on PTE has focused on adult populations, and consequently there is a paucity of information regarding paediatric cohorts. Additionally, there is considerable heterogeneity surrounding the reported incidence of PTE following childhood TBI in the current literature. The primary aim of our study is to summarise reported PTE incidences in paediatric populations to derive an accurate estimate of the global incidence of PTE following childho..View full abstract
While this project received no specific funding, the authors are currently supported by funding from the National Health and Medical Research Council of Australia (NHMRC), the US Department of Defense, and Monash University Central Clinical School.