Journal article
NMR spectroscopy of lipidic cubic phases
S Rajput, S Yao, DW Keizer, MA Sani, F Separovic
Biophysical Reviews | SPRINGERNATURE | Published : 2022
Abstract
Lipidic cubic phase (LCP) structures have been used for stabilisation and crystallisation of membrane proteins and show promising properties as drug carriers. In this mini-review, we present how NMR spectroscopy has played a major role in understanding the physico-chemical properties of LCPs and how recent advances in pulsed field gradient NMR techniques open new perspectives in characterising encapsulated molecules.
Grants
Funding Acknowledgements
The authors acknowledge the Bio21 NMR Facility for providing the facilities to carry out study of LCPs.