Journal article

NMR spectroscopy of lipidic cubic phases

S Rajput, S Yao, DW Keizer, MA Sani, F Separovic

Biophysical Reviews | Springer Science and Business Media LLC | Published : 2021

Abstract

Lipidic cubic phase (LCP) structures have been used for stabilisation and crystallisation of membrane proteins and show promising properties as drug carriers. In this mini-review, we present how NMR spectroscopy has played a major role in understanding the physico-chemical properties of LCPs and how recent advances in pulsed field gradient NMR techniques open new perspectives in characterising encapsulated molecules.