Journal article

Radiolabelled Peptides: Optimal Candidates for Theranostic Application in Oncology

AJ Hall, MB Haskali

Australian Journal of Chemistry | CSIRO PUBLISHING | Published : 2022

Abstract

Theranostics are drugs suitable for use in both diagnostic and therapeutic applications, and have played an important role in the advancement of modern nuclear medicine. This review explains key elements that are common to successful theranostics and highlights significant developments in the field, including our own. Specific focus is given to peptides and those features that make them most suitable for theranostic application, as well as some key radioisotopes owing to their favourable properties and high clinical utility. This report provides an overview of the techniques at the researcher's disposal, how they have been applied to current clinically significant targets, and how they might..

View full abstract

University of Melbourne Researchers

Grants

Awarded by Peter MacCallum Cancer Centre through Peter MacCallum Cancer Foundation


Awarded by National Health and Medical Research Council (NHMRC)


Funding Acknowledgements

Some parts of our work described in this review were funded by the Peter MacCallum Cancer Centre through Peter MacCallum Cancer Foundation Grant #1728 and the National Health and Medical Research Council (NHMRC) for New Investigator grant funding (APP1158863).