Journal article

Options for the Treatment of Mucinous Ovarian Carcinoma

Olivia Craig, Carolina Salazar, Kylie L Gorringe

CURRENT TREATMENT OPTIONS IN ONCOLOGY | SPRINGER | Published : 2021

Abstract

OPINION STATEMENT: Complete surgical resection is the gold-standard treatment for all mucinous ovarian carcinoma (MOC) cases. Advanced-stage disease is often additionally treated with adjuvant platinum-based chemotherapy; however, these were developed largely against the more common high-grade serous ovarian carcinoma and have low efficacy in treating MOC. More effective therapeutics are needed to treat late-stage and platinum-resistant tumors; however, traditional drug development and clinical trial paradigms are a major challenge for such a rare disease. New approaches to support evidence-based treatment decisions are required, such as registry trials. Recently, a number of targeted therap..

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