Journal article

Thunderstorm asthma in seasonal allergic rhinitis: The TAISAR study

JA Douglass, C Lodge, S Chan, A Doherty, JA Tan, C Jin, A Stewart, AM Southcott, A Gillman, J Lee, D Csutoros, L Hannan, L Ruane, S Barnes, L Irving, NS Harun, P Lachapelle, K Spriggs, M Sutherland, K See Show all

Journal of Allergy and Clinical Immunology | MOSBY-ELSEVIER | Published : 2022

Abstract

Background: Asthma epidemics associated with thunderstorms have had catastrophic effects on individuals and emergency services. Seasonal allergic rhinitis (SAR) is present in the vast majority of people who develop thunderstorm asthma (TA), but there is little evidence regarding risk factors for TA among the SAR population. Objective: We sought to identify risk factors for a history of TA and hospital presentation in a cohort of individuals with SAR. Methods: This multicenter study recruited adults from Melbourne, Australia, with a past diagnosis of TA and/or self-reported SAR. Clinical information, spirometry results, white blood cell count, ryegrass pollen–specific (RGP-sp) IgE concentrati..

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Funding Acknowledgements

Supported by a grant from the Medical Research Future Fund?s Rapid Applied Research Translation program in conjunction with the Melbourne Academic Centre for Health (GO162-MACH) . The study funder had no role in the study design; collection, analysis, and interpretation of data; writing of the report; and decision to submit for publication. All authors had full access to all data in the study and accept responsibility for submission of the final draft.