Journal article
The Batman and Robin of liver-stage immunity to malaria
WR Heath, LE Holz, D Fernandez-Ruiz
Trends in Parasitology | CELL PRESS | Published : 2022
Abstract
Malaria parasites replicate within the liver shortly after infection. This stage can be controlled by CD8 T cells, but which subsets undertake this function is unclear. Lefebvre et al. now elegantly show that effector memory T (TEM) cells are avid participants, working as a dynamic duo with liver tissue-resident memory T (TRM) cells to combat infection.
Grants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
W.R.H. is supported by an National Health and Medical Research Council (NHMRC) fellowship (APP1154457).