Journal article

The Batman and Robin of liver-stage immunity to malaria.

William R Heath, Lauren E Holz, Daniel Fernandez-Ruiz

Trends Parasitol | Elsevier BV | Published : 2021


Malaria parasites replicate within the liver shortly after infection. This stage can be controlled by CD8 T cells, but which subsets undertake this function is unclear. Lefebvre et al. now elegantly show that effector memory T (TEM) cells are avid participants, working as a dynamic duo with liver tissue-resident memory T (TRM) cells to combat infection.