Journal article

A Comparison of PROPr and EQ-5D-5L Value Sets

T Pan, B Mulhern, R Viney, R Norman, J Hanmer, N Devlin

Pharmacoeconomics | Published : 2022

Open access

Abstract

Objectives: The EQ-5D-5L and its value sets are widely used internationally. However, in the US and elsewhere, there is growing use of PROMIS, which has a value set (PROPr) based on the stated preferences of the US population. This paper aims to compare the characteristics of EQ-5D-5L and PROPr value sets and to highlight potential implications for users. Methods: US, Australian and English value sets were used for EQ-5D-5L. PROPr utilities were calculated based on PROMIS-29 + 2. We examined, in each case, (i) the characteristics (e.g. range of values, number of unique values) and distribution of all possible ‘theoretical’ utilities; (ii) dimension/domain importance ranking by the utility of..

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University of Melbourne Researchers

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Funding Acknowledgements

This work was funded by the EuroQol Research Foundation. Opinions expressed in the paper are those of the authors and are not necessarily those of the EuroQol Group. The authors would like to thank Qilin Yu, PhD candidate at The University of Melbourne, for his help and advice on generating all the 'theoretical' possible health states in Python v3.8. We would like to thank Ernest H. Law, PhD, Pfizer Inc., for his discussion and comments on this paper and participants at the 37th EuroQol Plenary Meeting, 16-17 September 2020, for their questions and comments.