Journal article

Greater mastery is associated with lower depression risk in a large international cohort of people with multiple sclerosis over 2.5 years

Sandra Neate, Afaf Humam, Nupur Nag, George A Jelinek, Steve Simpson-Yap

QUALITY OF LIFE RESEARCH | SPRINGER | Published : 2021

Abstract

BACKGROUND: Mastery is the extent to which an individual perceives their life circumstances as being under their control and not predominantly influenced by external factors. The relationship of mastery with clinical outcomes in people with multiple sclerosis (pwMS) has not been well-researched. We assessed the relationships of mastery with fatigue, disability, relapse number, and depression risk among pwMS over 2.5 years' follow-up. METHODS: Data from the Health Outcomes and Lifestyle in a Sample of people with Multiple sclerosis study, among 839 participants who completed the 2.5 and 5-year reviews, were analysed. Mastery was measured by the Pearlin Mastery Scale, fatigue by Fatigue Severi..

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