Intensified partner notification and repeat testing can improve the effectiveness of screening in reducing Chlamydia trachomatis prevalence: a mathematical modelling study

Ben B Hui; Jane S Hocking; Sabine Braat; Basil Donovan; Christopher K Fairley; Rebecca Guy; Simone Spark; Anna Yeung; Nicola Low; David Regan

Journal article

Intensified partner notification and repeat testing can improve the effectiveness of screening in reducing Chlamydia trachomatis prevalence: a mathematical modelling study

Ben B Hui, Jane S Hocking, Sabine Braat, Basil Donovan, Christopher K Fairley, Rebecca Guy, Simone Spark, Anna Yeung, Nicola Low, David Regan

SEXUALLY TRANSMITTED INFECTIONS | BMJ PUBLISHING GROUP | Published : 2022

DOI: 10.1136/sextrans-2021-055220

Abstract

Background The Australian Chlamydia Control Effectiveness Pilot (ACCEPt) was a cluster randomised controlled trial designed to assess the effectiveness of annual chlamydia testing through general practice in Australia. The trial showed that testing rates increased among sexually active men and women aged 16–29 years, but after 3 years the estimated chlamydia prevalence did not differ between intervention and control communities. We developed a mathematical model to estimate the potential longer-term impact of chlamydia testing on prevalence in the general population. Methods We developed an individual-based model to simulate the transmission of Chlamydia trachomatis in a heterosexual populat..

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University of Melbourne Researchers

Jane Hocking Author

Sabine Braat Author

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Grants

Awarded by Australian National Health and Medical Research Council (NHMRC)

Awarded by NHMRC

Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

This work was supported by the Australian National Health and Medical Research Council (NHMRC) Project Grant (1007937) and an NHMRC Partnership Grant (1056803). JSH is supported by an NHMRC Senior Research Fellowship Grant (1136117). CKF is supported by an NHMRC Leadership Investigator Grant (GNT1172900).