Journal article
Relationships between early postnatal cranial ultrasonography linear measures and neurobehaviour at term-equivalent age in infants born <30 weeks' gestational age
R Cuzzilla, JE Olsen, AL Eeles, SR Rogerson, PJ Anderson, FM Cowan, LW Doyle, JLY Cheong, AJ Spittle
Early Human Development | Published : 2022
Abstract
Background: The relationship between early postnatal brain development and neurobehaviour at term-equivalent age (TEA) remains uncertain. Aim: We aimed to explore relationships between early postnatal cranial ultrasonography (cUS) linear measures of brain size and brain growth with neurobehaviour at TEA in infants born <30 weeks' gestational age (GA). Study design: Prospective observational cohort study. Subjects: 137 infants born <30 weeks' GA without major brain injury on neonatal cUS. Outcome measures: Neurobehaviour at TEA assessed using the General Movements Assessment (GMA) and Hammersmith Neonatal Neurological Examination (HNNE). Results: The GMA was administered in 115/137 (84%) infa..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
Supported by grants from the National Health and Medical Research Council of Australia (Centre of Research Excellence #1060733, including PhD stipend to RC; Career Development Fellowship #1108714 to AJS; Project grant #1101035), the Medical Research Future Fund of Australia (Career Development Fellowship to JLYC #1141354) and the Victorian Government's Operational Infrastructure Support Program. We thank our research coordinators who did all the recruiting, Emma McInnes for her contributions to neurobehavioural assessments, the clinical staff who performed all the cranial ultrasonography, and the infants and their families for their participation.