Journal article
Synthesizing Core Outcome Sets for outcomes research in cohort studies: a systematic review
Erica Musgrove, Loretta Gasparini, Katie McBain, Susan A Clifford, Simon A Carter, Helena Teede, Melissa Wake
PEDIATRIC RESEARCH | SPRINGERNATURE | Published : 2022
Abstract
Background: Life course studies are designed to “collect once, use multiple times” for observational and, increasingly, interventional research. Core Outcome Sets (COS) are minimum sets developed for clinical trials by multi-stakeholder consensus methodologies. We aimed to synthesize published COS that might guide outcomes selection for early life cohorts with an interventional focus. Methods: We searched PubMed, Medline, COMET, and CROWN for COS published before January 2021 relevant to four life stages (pregnancy, newborns, children <8 years, and parents (adults aged 18–50 years)). We synthesized core outcomes into overarching constructs. Results: From 46 COS we synthesized 414 core outcom..
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Awarded by Australian National Health & Medical Research Council (NHMRC) Principal Research Fellowship
Awarded by NHMRC
Awarded by National Health and Medical Research Council of Australia
Funding Acknowledgements
No specific funding was available for this study. Generation Victoria is supported by the Paul Ramsay Foundation, Victorian Government, Murdoch Children's Research Institute (MCRI), and The Royal Children's Hospital Foundation. Research at the MCRI is supported by the Victorian Government's Operational Infrastructure Support Program. M.W. is supported by Australian National Health & Medical Research Council (NHMRC) Principal Research Fellowship 1160906. H.T. is supported by an NHMRC Practitioner Fellowship funded by the Australian Medical Research Future Fund. S.A. Carter is supported by NHMRC Post-graduate Scholarship 1168994.