An unusual cause of colonic ulceration

Abstract

The features are consistent with intestinal Behçet’s disease (BD). BD is a multisystemic immune-mediated inflammatory disorder characterised by recurrent painful oral and genital ulcers.1 It comprises deposition of immune complexes in veins and arteries of all sizes, and may affect multiple viscera, including the gastrointestinal (GI), neurological and musculoskeletal systems.1 It shares several overlapping intestinal and extraintestinal manifestations with Crohn’s disease.2 Symptoms of intestinal BD include abdominal pain, haematochezia and weight loss.3 Oral ulcers usually precede the onset of GI symptoms.3 Altered bowel habit is less common in intestinal BD. HLA-B51 is associated with BD,..