Relationships between global functioning and neuropsychological predictors in subjects at high risk of psychosis or with a recent onset of depression

L Squarcina; L Kambeitz-Ilankovic; C Bonivento; C Prunas; L Oldani; J Wenzel; A Ruef; D Dwyer; A Ferro; S Borgwardt; J Kambeitz; TK Lichtenstein; E Meisenzahl; C Pantelis; M Rosen; R Upthegrove; LA Antonucci; A Bertolino; R Lencer; S Ruhrmann; RRK Salokangas; F Schultze-Lutter; K Chisholm; A Stainton; SJ Wood; N Koutsouleris; P Brambilla

Journal article

Relationships between global functioning and neuropsychological predictors in subjects at high risk of psychosis or with a recent onset of depression

L Squarcina, L Kambeitz-Ilankovic, C Bonivento, C Prunas, L Oldani, J Wenzel, A Ruef, D Dwyer, A Ferro, S Borgwardt, J Kambeitz, TK Lichtenstein, E Meisenzahl, C Pantelis, M Rosen, R Upthegrove, LA Antonucci, A Bertolino, R Lencer, S Ruhrmann Show all

World Journal of Biological Psychiatry | TAYLOR & FRANCIS LTD | Published : 2022

DOI: 10.1080/15622975.2021.2014955

Abstract

Objective: Psychotic disorders are frequently associated with decline in functioning and cognitive difficulties are observed in subjects at clinical high risk (CHR) for psychosis. In this work, we applied automatic approaches to neurocognitive and functioning measures, with the aim of investigating the link between global, social and occupational functioning, and cognition. Methods: 102 CHR subjects and 110 patients with recent onset depression (ROD) were recruited. Global assessment of functioning (GAF) related to symptoms (GAF-S) and disability (GAF-D). and global functioning social (GF-S) and role (GF-R), at baseline and of the previous month and year, and a set of neurocognitive measures..

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University of Melbourne Researchers

Dom Dwyer Author

Christos Pantelis Author

Alex Stainton Author

Stephen Wood Author

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Grants

Awarded by Seventh Framework Programme

Funding Acknowledgements

PRONIA is a Collaboration Project funded by the European Union under the 7th Framework Programme [grant agreement no 602152]. C Pantelis was supported by a National Health and Medical Research Council (NHMRC) Senior Principal Research Fellowship (1105825), an NHMRC L3 Investigator Grant (1196508), and NHMRC-EU grant (1075379).