De novo design of CRISPR-Cas13b enables efficient silencing of SARS-CoV-2 variants and tumour pathogenic RNAs with near single-base precision

Wenxin Hu, Wei Zhao, Amit Kumar, Gurjeet Jagjeet Singh, Shijiao Qi, Josh Casan, Carolyn Shembery, Danielle Fong, Jennifer M Zerbato, Jori Symons, Rajeev Rudraraju, Damian Purcell, Michelle Haber, Ilia Voskoboinik, Paul G Ekert, Sharon Lewin, Joseph Trapani, Mohamed Fareh