Development and application of Diels-Alder adducts displaying AIE properties

TL Gialelis; TC Owyong; S Ding; W Li; M Yu; NM O'Brien-Simpson; Z Zhao; JM White; B Yao; Y Hong

Journal article

Development and application of Diels-Alder adducts displaying AIE properties

TL Gialelis, TC Owyong, S Ding, W Li, M Yu, NM O'Brien-Simpson, Z Zhao, JM White, B Yao, Y Hong

Cell Reports Physical Science | CELL PRESS | Published : 2022

DOI: 10.1016/j.xcrp.2022.100766

Abstract

Exploring organic reactions to construct novel molecules with aggregation-induced emission (AIE) features is an essential branch of AIE research. The fast-paced application of AIE materials in various disciplines, including photoelectricity, molecular biology, medicine, and materials science, has led to an ever-growing need for new AIE molecules. Unlike the synthesis of most “earlier generations” of AIE fluorogens (AIEgens) that require tedious and harsh reactions, chemists now shift their synthetic focus to a selection of reliable and straightforward reactions. The Diels-Alder reaction has been overlooked in this field. Herein, we report a catalyst-free Diels-Alder reaction between 1,3-diph..

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University of Melbourne Researchers

Wenyi Li Author

Neil O'Brien-Simpson Author

Jonathan White Author

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Grants

Awarded by Australian Research Council

Funding Acknowledgements

We thank Dr. Wallace W.H. Wong (University of Melbourne) for helpful discussion; LIMS Bioimaging Platform and Comprehensive Proteomics Platform for the access to microscopes, mass spectrometer, and NMR facilities; and Australian Synchrotron for beamtime via the Collaborative Access Program (proposal 13618b). This work was supported by funding from Australian Research Council (FT210100271), National Health and Medical Research Council (APP1161803), and Australia-China Science and Research Fund-Joint Research Centre on Personal Health Technologies (ACSRF65777).