Brain Morphological Characteristics of Cognitive Subgroups of Schizophrenia-Spectrum Disorders and Bipolar Disorder: A Systematic Review with Narrative Synthesis

JA Karantonis; SP Carruthers; KE Burdick; C Pantelis; M Green; SL Rossell; ME Hughes; V Cropley; TE Van Rheenen

Journal article

Brain Morphological Characteristics of Cognitive Subgroups of Schizophrenia-Spectrum Disorders and Bipolar Disorder: A Systematic Review with Narrative Synthesis

JA Karantonis, SP Carruthers, KE Burdick, C Pantelis, M Green, SL Rossell, ME Hughes, V Cropley, TE Van Rheenen

Neuropsychology Review | SPRINGER | Published : 2023

DOI: 10.1007/s11065-021-09533-0

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Abstract

Despite a growing body of research, there is yet to be a cohesive synthesis of studies examining differences in brain morphology according to patterns of cognitive function among both schizophrenia-spectrum disorder (SSD) and bipolar disorder (BD) individuals. We aimed to provide a systematic overview of the morphological differences—inclusive of grey and white matter volume, cortical thickness, and cortical surface area—between cognitive subgroups of these disorders and healthy controls, and between cognitive subgroups themselves. An initial search of PubMed and Scopus databases resulted in 1486 articles of which 20 met inclusion criteria and were reviewed in detail. The findings of this re..

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University of Melbourne Researchers

Christos Pantelis Author

Vanessa Cropley Author

Tamsyn van Rheenen Author

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Grants

Awarded by Melbourne Institute, University of Melbourne

Funding Acknowledgements

Open Access funding enabled and organized by CAUL and its Member Institutions. Financial support from the National Health and Medical Research Council (NHMRC) provided salary support to TVR (Early Career Fellowship 1088785), SR (Senior Research Fellowship 1154651) and CP (Senior Principal Research Fellowships 628386 and 1105825); and Swinburne University/the Australian Government provided postgraduate scholarships to JK and SC. The authors would also like to acknowledge specific financial support of the NHMRC (1060664), Henry Freeman Trust, Jack Brockhoff Foundation, University of Melbourne, Barbara Dicker Brain Sciences Foundation, Rebecca L Cooper Foundation and the Society of Mental Health Research.