Epileptic seizure control during and after pregnancy in Australian women

Abstract

Objectives: To study factors that affected previous epileptic seizure control throughout pregnancy, during labour, and in the post-natal weeks. Materials & Methods: Analysis of data concerning seizure freedom that was available at various stages of 2337 pregnancies in the Raoul Wallenberg Australian Pregnancy Register of Antiepileptic Drugs, mainly employing multiple variable logistic regression techniques. Results: Based on data available at the outset of pregnancy, the risk of seizure-affected that is, not seizure-free pregnancy was statistically significantly (p <.05) higher in pregnancies where there was previously uncontrolled epilepsy (78.1% vs. 20.8%) and focal epilepsy (51.3% vs. 39...