The association between the inflammatory potential of diet and risk of developing, and survival following, a diagnosis of ovarian cancer

CM Nagle; T Ibiebele; N Shivappa; JR Hebert; A DeFazio; PM Webb

Journal article

The association between the inflammatory potential of diet and risk of developing, and survival following, a diagnosis of ovarian cancer

CM Nagle, T Ibiebele, N Shivappa, JR Hebert, A DeFazio, PM Webb

EUROPEAN JOURNAL OF NUTRITION | SPRINGER HEIDELBERG | Published : 2019

DOI: 10.1007/s00394-018-1779-x

Abstract

PURPOSE: Inflammation has been implicated in ovarian carcinogenesis. This study evaluated two dietary indices: the Dietary Inflammatory Index (DII®) and the Empirical Dietary Inflammatory Pattern (EDIP), in relation to risk of developing, and survival following, a diagnosis of ovarian cancer. METHODS: Data came from the Australian Ovarian Cancer Study (1375 cases, 1415 population controls). DII and EDIP scores were computed from dietary information obtained using a semiquantitative food-frequency questionnaire. Logistic regression was used to assess the association between DII and EDIP scores and risk of ovarian cancer and proportional hazards models were used for survival analysis. RESULTS:..

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University of Melbourne Researchers

David Bowtell Author

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Grants

Awarded by U.S. Army Medical Research and Materiel Command

Awarded by National Health and Medical Research Council (NHMRC) of Australia

Funding Acknowledgements

The Australian Ovarian Cancer Study was supported by the U.S. Army Medical Research and Materiel Command (DAMD17-01-1-0729), the National Health and Medical Research Council (NHMRC) of Australia (Grants 400281, 400413, 199600), the Cancer Councils of Victoria, Queensland, New South Wales, South Australia and Tasmania and the Cancer Foundation of Western Australia. CMN and TII were supported by NHMRC Program Grant, PMW by a fellowship from the NHMRC and AdeF was funded by the University of Sydney Cancer Research Fund and the Cancer Institute NSW through the Sydney-West Translational Cancer Research Centre. The funders had no role in the design, analysis or writing of this article.