Journal article
CD4 chimeric antigen receptor T cells in for the long journey
AXY Chen, EB Derrick, PA Beavis, IG House
Immunology and Cell Biology | Published : 2022
DOI: 10.1111/imcb.12545
Abstract
In a recently published article, Melenhorst et al. performed a longitudinal analysis on chimeric antigen receptor (CAR) T cells isolated from patients over 10 years after therapy, revealing expansion of a long-lived CD4+ CAR T-cell population with a cytotoxic phenotype.
Grants
Awarded by AstraZeneca
Funding Acknowledgements
Amanda XY Chen is supported by an Australian Government Research Training Program Stipend Scholarship and a Peter MacCallum Cancer Foundation Rosie Lew Postgraduate Scholarship. Paul A Beavis is supported by a Victorian Cancer Agency Mid-Career Fellowship (2021-Current, MCRF20011). Imran G House is supported by a Victorian Cancer Agency Early Career Fellowship (ECRF20017).