The minimal clinically important difference in the treadmill six-minute walk test in active women with breast cancer during and after oncological treatments

Abstract

Purpose: To examine the minimal clinically important difference (MCID) in the treadmill 6-minute walk test (6MWT) in women with breast cancer. Materials and methods: A secondary analysis of cross-sectional data from 112 women who were undergoing chemotherapy or had undergone anticancer treatment was conducted. Participants completed the 6MWT on a treadmill and the European Organization for Research and Treatment of Cancer Questionnaire (EORTC-QLQ-C30) twice, eight weeks apart. Change in the physical function domain of the EORTC-QLQ-C30 was used to classify the “positive change” subgroup (≥5 points difference) and the “unchanged” subgroup (<5 points difference). This was combined with the dis..