Effect of Bariatric Surgery on Risk of Complications After Total Knee Arthroplasty: A Randomized Clinical Trial

Michelle M Dowsey; Wendy A Brown; Angela Cochrane; Paul R Burton; Danny Liew; Peter F Choong

Journal article

Effect of Bariatric Surgery on Risk of Complications After Total Knee Arthroplasty: A Randomized Clinical Trial

Michelle M Dowsey, Wendy A Brown, Angela Cochrane, Paul R Burton, Danny Liew, Peter F Choong

Jama Network Open | American Medical Association | Published : 2022

DOI: 10.1001/jamanetworkopen.2022.6722

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Abstract

Importance: People with severe obesity who undergo a total knee arthroplasty (TKA) for osteoarthritis (OA) are at higher risk of short-term and long-term complications compared with people with reference (<30) body mass index (BMI; weight in kilograms divided by height in meters squared). It is not known whether weight loss before TKA modifies this risk. Objective: To determine whether outcomes are improved by undergoing bariatric surgery before TKA in people with BMI greater than or equal to 35 and end-stage OA. Design, Setting, and Participants: This parallel-group, assessor-blinded, randomized clinical trial was conducted between May 2012 and June 2020 with a minimum follow-up of 12 m..

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University of Melbourne Researchers

Michelle Dowsey Author

Ange Cochrane Author

Peter Choong Author

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Grants

Awarded by Johnson and Johnson

Funding Acknowledgements

This work was supported by a National Health and Medical Research Council Project Grant (GNT1019866). Dr Dowsey is supported by a National Health and Medical Research Council Career Development Fellowship (APP1122526). Dr Choong is supported by a National Health and Medical Research Council Practitioner Fellowship. The Lap-Band device was provided at a reduced price by Allergan.