Effects of adding aerobic physical activity to strengthening exercise on hip osteoarthritis symptoms: protocol for the PHOENIX randomised controlled trial

M Hall; K Allison; RS Hinman; KL Bennell; L Spiers; G Knox; M Plinsinga; DM Klyne; F McManus; KE Lamb; R Da Costa; NJ Murphy; FL Dobson

Journal article

Effects of adding aerobic physical activity to strengthening exercise on hip osteoarthritis symptoms: protocol for the PHOENIX randomised controlled trial

M Hall, K Allison, RS Hinman, KL Bennell, L Spiers, G Knox, M Plinsinga, DM Klyne, F McManus, KE Lamb, R Da Costa, NJ Murphy, FL Dobson

BMC Musculoskeletal Disorders | BMC | Published : 2022

DOI: 10.1186/s12891-022-05282-0

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Abstract

Background: Hip osteoarthritis (OA) is a leading cause of musculoskeletal pain. Exercise is a core recommended treatment. Most evidence is based on muscle-strengthening exercise, but aerobic physical activity has potential to enhance clinical benefits. The primary aim of this study is to test the hypothesis that adding aerobic physical activity to a muscle strengthening exercise leads to significantly greater reduction in hip pain and improvements in physical function, compared to a lower-limb muscle strengthening exercise program alone at 3 months. Methods: This is a superiority, 2-group, parallel randomised controlled trial including 196 people with symptomatic hip OA from the community. F..

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Grants

Awarded by U.S. Department of Defense

Funding Acknowledgements

This study is funded by the Australian National Health and Medical Research Council (Project Grant #APP1159045). This study protocol underwent external peer-review by the funding source. Study protocol underwent external peer-review by the funding source. MH is supported by a National Health and Medical Research Council (NHMRC) Investigator Grant Emerging Leader 1 (#1172928). RSH is supported by a NHMRC Senior Research Fellowship (#1154217). KLB is supported by a NHMRC Investigator Grant Leadership 2 (#1174431). DMK is supported by the Assistant Secretary of Defense for Health Affairs, endorsed by the U.S. Department of Defense through the FY19 Chronic Pain Management Research Program (Award No. W81XWH2010909). The funding sources had no role in the design of this study and will not have any role during its execution, analyses, interpretation of the data, or decision to submit results.