Journal article
Recommendations for standardized definitions, clinical assessment, and future research in pediatric clinically unsuspected venous thromboembolism: Communication from the ISTH SSC subcommittee on pediatric and neonatal thrombosis and hemostasis
M Betensky, K Kulkarni, M Rizzi, S Jones, LR Brandão, EVS Faustino, NA Goldenberg, A Sharathkumar
Journal of Thrombosis and Haemostasis | Published : 2022
DOI: 10.1111/jth.15731
Abstract
Clinically unsuspected venous thromboembolism (VTE) in children is defined as a VTE diagnosed via imaging test performed for surveillance (i.e., with an intent to identify clinically silent VTEs) or incidentally found (most often via imaging performed for evaluation of regional pathology unrelated to VTE) in the absence of any VTE-associated signs or symptoms. Our understanding of the clinical significance of these events in children is limited by a paucity of data on the epidemiology and outcomes of this complication. There is an urgent need for further research in this area to inform optimal management. Recognizing this knowledge gap, this Task Force has previously published a systematic r..
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Awarded by National Institutes of Health
Funding Acknowledgements
M. B. receives consulting fees from Janssen Pharmaceuticals; N. A. G. receives consulting fees from Bayer, Boerhinger Ingelheim, and Anthos for advisory board activities, from Novartis for data and safety monitoring board activities, from Daiichi Sankyo for steering committee activities, from the university--affiliated Academic Research Organization CPC Clinical Research for data and safety monitoring board activities for clinical trials sponsored by Bristol Myers Squibb and Pfizer, and he also receives research and salary support from the U.S. National Institutes of Health (NIH), via a U01 award; E. V. S. F. receives funding from the American Heart Association, NIH and Grifols for research support, and consulting fees from Boehringer Ingelheim for advisory board activities; A. S., M. R., L. R. B., K. K., and S. J. declare no potential conflicts of interest related to this work.