Journal article

Nanostructured particles assembled from natural building blocks for advanced therapies

Y Ju, H Liao, JJ Richardson, J Guo, F Caruso

Chemical Society Reviews | Published : 2022

Abstract

Advanced treatments based on immune system manipulation, gene transcription and regulation, specific organ and cell targeting, and/or photon energy conversion have emerged as promising therapeutic strategies against a range of challenging diseases. Naturally derived macromolecules (e.g., proteins, lipids, polysaccharides, and polyphenols) have increasingly found use as fundamental building blocks for nanostructured particles as their advantageous properties, including biocompatibility, biodegradability, inherent bioactivity, and diverse chemical properties make them suitable for advanced therapeutic applications. This review provides a timely and comprehensive summary of the use of a broad r..

View full abstract

University of Melbourne Researchers

Grants

Awarded by Australian Research Council


Funding Acknowledgements

This research was supported by the Australian Research Council Discovery Project (DP210103114). F. C. acknowledges the award of a National Health and Medical Research Council Senior Principal Research Fellowship (GNT1135806). Y. J. acknowledges the award of a Vice-Chancellor's Postdoctoral Fellowship from RMIT University. J.J.R acknowledged the Japan Society for the Promotion of Science (JSPS) for his fellowship (Grant No. 20F20373). J. G. acknowledges the award of National Talents Program, National Natural Science Foundation of China (22178233), Talents Program of Sichuan Province, Double First Class University Plan of Sichuan University, and State Key Laboratory of Polymer Materials Engineering (Grant No. sklpme 2020-03-01). The authors acknowledge Dr Yunxiang He for helpful discussion and assistance with Fig. 33 and 34.